Alagille Syndrome
Pathogenesis and Clinical Management
(Sprache: Englisch)
This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and...
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Klappentext zu „Alagille Syndrome “
This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options.Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that will help guide patient management and stimulate investigative efforts.
Inhaltsverzeichnis zu „Alagille Syndrome “
The Alagille Syndrome: Overview and Introduction.- Bile Duct Development and the Notch Signaling Pathway.- Genetics of Alagille Syndrome.- Liver Disease in Alagille Syndrome.- Transplant Considerations in Alagille Syndrome.- Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille Syndrome.- Vascular Manifestations in Alagille Syndrome.- The Renal Sequelae of Alagille Syndrome as a Product of Altered Notch Signaling During Kidney Development.- Skeletal Involvement in Alagille Syndrome.- Immune Dysregulation in Alagille Syndrome: A Feature of the Evolving Phenotype.- Health-Related Quality of Life and Neurocognition in Alagille Syndrome.- Future Therapeutic Approaches for Alagille Syndrome.
Autoren-Porträt
Binita M. Kamath, MBBChir MRCP MTRThe Hospital for Sick ChildrenDivision of Gastroenterology, Hepatology and Nutrition Toronto, ONCanadaKathleen M. Loomes, MDChildren's Hospital of PhiladelphiaDivision of Gastroenterology, Hepatology and NutritionDepartment of PediatricsPhiladelphia, PAUSA
Bibliographische Angaben
- 2019, Softcover reprint of the original 1st ed. 2018, XIV, 198 Seiten, 31 farbige Abbildungen, Masse: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Binita M. Kamath, Kathleen M. Loomes
- Verlag: Springer, Berlin
- ISBN-10: 3030068781
- ISBN-13: 9783030068783
Sprache:
Englisch
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