Biological Reaction Engineering

Part I Principles of Bioreactor Modeling Modeling Principles Basic Bioreactor Concepts Biological Kinetics Bioreactor Modeling Mass Transfer Diffusion and Biological Reaction in Immobilized Biocatalyst Systems Automatic Bioprocess Control Fundamental Basic Cell and Bioreactor Models Part II Dynamic Bioprocess Simulation Examples Using the BERKELEY MADONNA Simulation Language Biological Reaction Process Modeling Examples Simulation Examples of Biological Reaction Processes Using BERKELEY MADONNA Appendix: Using the Berkeley Madonna Language and Accessing the Simulation Examples

Elmar Heinzle is Senior Professor of Biochemical Engineering at the Saarland University in Saarbrücken, Germany. Having obtained his academic degrees from the Technical University of Graz, Austria, he spent a large fraction of his career at the Chemical Engineering Department of ETH-Zurich, Switzerland, before becoming Chair of Biochemical Engineering at the Saarland University. In 2003 he was Guest Professor at the Biotechnology Institute (University of Minnesota, St. Paul) and in 2004 at the Agricultural Department (University of Kyoto, Kyoto). Professor Heinzle published well over 200 scientific publications in bioreactor design, metabolic engineering and systems biology, mammalian cell culture, on-line analysis and control and design of sustainable processes. In his teaching in Biochemical and Chemical Engineering he is extensively using modelling. He has authored several books in these fields. Irving J. Dunn is retired from the ETH-Zurich, where he taught and did research in the area of biochemical engineering for over thirty years, within the Chemical Engineering Dept. His degrees are from the University of Washington and Princeton University. Dr. Dunn has published widely in his field, ranging from bioreactor design, process control, animal cell culture, and specialized wastewater treatment. His teaching and research has featured the use of modelling and simulation and has resulted in the publication of three textbooks: Biological Reaction Engineering, Dynamics of Environmental Bioprocesses and Chemical Engineering Dynamics. In 1981 he founded the renowned International Modelling and Simulation Courses in Braunwald, Switzerland. John Ingham is now retired from Chemical Engineering at Bradford University U.K. The first of a long series of courses on the Modelling and Simulation of Dynamical Chemical Engineering Systems was begun there in 1974, sponsored by the Institution of Chemical Engineers and inspired by leave of absence at the ETH Zurich. Research areas

"...ist das Buch eine echte Bereicherung und führt hoffentlich bei den Lesern zum angestrebten Schub an Interesse und Fähigkeit. Ich werde es jedenfalls in Griffweite neben dem Laptop postieren und den Studierenden in den einschlägigen Vorlesungen empfehlen."
 
C. Posten, Karlsruhe
CIT 3/04
 
"Besonders hervorzuheben ist der für ein Lehrbuch sehr erfreuliche durchgehend praktische Bezug. Das Buch ist meines Erachtens besonders gut für angehende Fachhochschulingenieure sowie für Studenten in Nebenfächern geeignet. Darüber hinaus kann es als erste Lektüre für denjenigen dienen, der sich in das Fachgebiet einarbeiten möchte."
 
Chemie Ingenieur Technik, B. Nienhaus, Frankfurt