Epigenetics of Aging

TABLE OF CONTENTS 1. Epigenetics and the Aging Process Trygve O. Tollefsbol PART I: DNA Methylation and Histone Modifications in Aging 2. Age-related Genomic Hypomethylation Igor P. Pogribny and Boris F. Vanyushin 3. Gene-specific Hypermethylation in Aging Adebayo D. Akintola and Alan K. Parrish 4. Aging and Non-sirtuin Histone Modifications Inga Kadish 5. Sirtuins and Aging Yuqing Dong and Sige Zou 6. Chromatin in Senescent Cells: a Conduit for the Anti-aging effects of Wnt-signaling? Gowrishankar Banumathy and Peter D. Adams 7. S-AdenosylMethionine: Simple Agent of Methylation and Secret to Aging and Metabolism? Wil A.M. Loenen PART II: Other Epigenetic Processes and Aging 8. Polycomb Group of Genes and the Epigenetics of Aging Krishnaveni Mishra and Rakesh K. Mishra 9. Chromosomal Position Effect and Aging Eric Gilson and Frederique Magdinier 10. Noncoding RNA for Pre-symptomatic Diagnosis of Age-dependent Disease Eugenia Wang PART III: Impact of Epigenetics on Aging 11. Telomerase Control by Epigenetic Processes in Cellular Senescence Huaping Chen and Trygve O. Tollefsbol 12. Telomeres, Epigenetics and Aging J. Arturo Londono-Vallejo 13. Contributions of Tumor Suppressors to the Epigenetic Regulation of Aging Cells Pinaki Base, Amudha Ganapathy, and Karl Riabowol 14. Epigenetic Drift and Aging Ester Lara, Vincenzo Calvanese, and Mario F. Fraga 15. Role of Epigenetics in Age-related Long-term Memory Loss J. Tyson DeAngelis and Trygve O. Tollefsbol PART IV: Epigenetics of Age-related Diseases 16. The Epigenetics of Age-related Cancers Kristen H. Taylor, Lynda B. Bennett, Gerald L. Arthur, Huidong Shi, and Charles W. Caldwell 17. DNA Methylation and Alzheimer's Disease Thomas van Groen 18. DNA Methylation, Age-related Immune Defects, and Autoimmunity Jorg J. Goronzy, Guangjin Li, and Cornelia M. Weyand 19. Epigenetic Silencing of Progeroid Syndromes Ruben Agrelo 20. DNA Methylation and Osteoarthritis Helmtrud I. Roach PART V: Epigenetic Interventions and Aging 21.

From the reviews:

"This nearly 500-pages thick book covers almost everything around the topic of how aging and age-related diseases might be affected by epigenetic processes. ... Understanding the drifting and stochastic nature of aging is crucial for making any use of the epigenetic pathways to intervention, and for developing future directions in research. I surely recommend this book, which will help to open up many doors towards achieving that." (Suresh I. S. Rattan, Biogerontology, Vol. 12, 2011)

From the reviews:"This nearly 500-pages thick book covers almost everything around the topic of how aging and age-related diseases might be affected by epigenetic processes. ... Understanding the drifting and stochastic nature of aging is crucial for making any use of the epigenetic pathways to intervention, and for developing future directions in research. I surely recommend this book, which will help to open up many doors towards achieving that." (Suresh I. S. Rattan, Biogerontology, Vol. 12, 2011)