Genome Instability

The A-like Faker Assay for Measuring Yeast Chromosome III Stability.- The Chromosome Transmission Fidelity Assay for Measuring Chromosome Loss in Yeast.- Measuring Mutation Rates using the Luria-Delbrück Fluctuation Assay.- Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitized Single-Stranded DNA Reporter System in Budding Yeast.- Analyzing Genome Rearrangements in Saccharomyces cerevisiaen: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">.- High Resolution Mapping of Modified DNA Nucleobases using Excision Repair Enzymes.- Integrated Microarray-based Tools for Detection of Genomic DNA Damage and Repair Mechanisms.- Study of UV-induced DNA Repair Factor Recruitment: Kinetics and Dynamics.- Inserting Site-specific DNA Lesions into Whole Genomes.- A qPCR-based Protocol to Quantify DSB Resection.- Alkaline Denaturing Southern Blot Analysis to Monitor Double-strand Break Processing.- Single Molecule Analysis of Resection Tracks.- Mapping DNA Breaks by Next-generation Sequencing.- Genome-wide Profiling of DNA Double-strand Breaks by the BLESS and BLISS Methods.- DNA Replication Profiling using Deep Sequencing.- Quantitative Bromodeoxyuridine Immunoprecipitation Analyzed by High-Throughput Sequencing (qBrdU-seq or QBU).- Strand-specific Analysis of DNA Synthesis and ProteinsAssociation with DNA Replication Forks in Budding Yeast.- Analysis of Replicative Polymerase Usage by Ribonucleotide Incorporation.- Dynamic Architecture of Eukaryotic DNA Replication Forks in vivo, Visualized by Electron Microscopy.- A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation.- Single Cell Gel Electrophoresis for the Detection of Genomic Ribonucleotides.- Measuring the Levels of Ribonucleotides Embedded in Genomic DNA.- Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing.- Detection of DNA-RNA Hybrids in