Immunology and Psychiatry

Part I. Basic Science.- 1: Animal models based on immune challenge: the links to brain changes and psychiatric disorders.- 2: The prenatal immune activation model for schizophrenia and the role of stress in puberty.- 3: Rodent models of stress induced depression: the link between stress and immune system related changes.- 4. Experimental Human Endotoxemia, Sickness Behavior and Neuropsychiatric Diseases.- Part II. Translational Medicine.- 5. Mild encephalitis theory of psychiatric disorders.- 6. The role of Infection and autoimmune disorders for schizophrenia and depression: Consequences from a large-scale epidemiological study.- 7. Exposure to microorganisms and adult psychiatric disorders: proofs for causal relationship.- 8. Depression: From activation of immune-inflammatory pathways to oxidative-stress-induced autoimmune responses and neuroprogression.- 9. Immune system related markers changes in childhood neuropsychiatric disorders: cause and consequence.- 10. Cytokines and related metabolic biomarkers in adult neuropsychiatric disorders: possible roles in clinical application.- 11. Immune system changes play a role in the development of the metabolic syndrome in psychiatric disorders.- 12. The activation of microglia in severe neuropsychiatric disorders: Focus on infectious mechanisms and PET imaging.- 13. The role of inflammation in Tourette's Syndrome.- 14. The role of inflammation in Autism.- 15. The role of inflammation in Alzheimer's Disease.- Part III: Therapeutic application.- 16. Antidepressants: influence on immune system related parameters.- 17. Cyclooxygenase-2 inhibition in management of depression and schizophrenia.- 18. Poly-unsaturated fatty-acids in management of adult psychiatric disorders.

Norbert Müller

Ludwig-Maximilians-University Munich

Germany

Aye-Mu Myint

Ludwig-Maximilians-University Munich

Germany

Markus J. Schwarz

Klinikum der Universitaet Muenchen

Germany

"The editors and authors have produced an excellent, thought-provoking book. The primary audience includes psychiatrists, researchers in immunology and psychiatry, and anyone interested in the immunological contributions to psychopathology. ... This is an excellent book on an emerging and important area in psychiatry: the role of the immune system. Written and edited by internationally recognized experts, it is a welcome addition to the literature. I highly recommend it." (Michael Joel Schrift, Doody's Book Reviews, September, 2015)