Induced Pluripotent Stem Cells and Human Disease

- Analysis of Mitochondrial Dysfunction by Microplate Reader in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Disorders. - Generation and Hematopoietic Differentiation of Mesenchymal Stromal/Stem Cell-Derived Induced Pluripotent Stem Cell Lines for Disease Modeling of Hematopoietic and Immunological Diseases. - Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis. - Monitoring Axonal Degeneration in Human Pluripotent Stem Cell Models of Hereditary Spastic Paraplegias Patients. - Efficient Generation of Functional Hepatocytes from Human Induced Pluripotent Stem Cells for Disease Modeling and Disease Gene Discovery. - Autophagy Dysfunction as a Phenotypic Readout in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Diseases. - Derivation of Induced Pluripotent Stem Cell (iPSC) Lines from Patient-Specific Peripheral Blood Mononuclear Cells (PBMC) Using Episomal Vectors. - Differentiating Induced Pluripotent Stem Cells Toward Mesenchymal Stem/Stromal Cells. - A High-Efficiency Method for the Production of Endothelial Cells from Human Induced Pluripotent Stem Cells. - Image-Based Quantitation of Kainic Acid-Induced Excitotoxicity as a Model of Neurodegeneration in Human iPSC-Derived Neurons. - Amyloid beta (Abeta) ELISA of Human iPSC-Derived Neuronal Cultures. - Creating Cell Model 2.0 Using Patient Samples Carrying a Pathogenic Mitochondrial DNA Mutation: iPSC Approach for LHON. - CRISPR Guide RNA Library Screens in Human Induced Pluripotent Stem Cells. - Generation and Encapsulation of Human iPSC-Derived Vascular Smooth Muscle Cells for Proangiogenic Therapy. - Methods to Induce Small-Scale Differentiation of iPS Cells into Dopaminergic Neurons and to Detect Disease Phenotypes. - Modeling Early Neural Crest Development via Induction from hiPSC-Derived Neural Plate