Movement Disorders in Childhood

Section I. Overview 1. Basal Ganglia Anatomy, Biochemistry, and Physiology 2. Cerebellar Anatomy, Biochemistry, Physiology, and Plasticity 3. Classification of Movement Disorders 4. Diagnostic Evaluation of Children with Movement Disorders 5. Motor Assessments

Section II. Developmental Movement Disorders 6. Transient and Developmental Movement Disorders

Section III. Paroxysmal Movement Disorders 7. Tics and Tourette Syndrome 8. Motor Stereotypies 9. Paroxysmal Dyskinesias

Section IV. Hyperkinetic and Hypokinetic Movement Disorders 10. Chorea, Athetosis, and Ballism 11. Dystonia 12. Myoclonus 13. Tremor 14. Ataxia 15. Parkinsonism 16. Hereditary Spastic Paraplegia

Section V. Selected Secondary Movement Disorders 17. Metabolic Disorders with Associated Movement Abnormalities 18. Movement Disorders in Autoimmune Diseases 19. Movement Disorders in Sleep 20. Cerebral Palsy 21. Movement Disorders and Neuropsychiatric Conditions 22. Drug-Induced Movement Disorders in Children 23. Functional Movement Disorders

Appendix A: Drug Appendix Appendix B: Search Strategy for Genetic Movement Disorders

Harvey S. Singer MD is currently Professor Emeritus at the Johns Hopkins University School of Medicine and active faculty member at the Kennedy Krieger Institute. He grew up in the Bronx and Long Island, went to college and medical school in Ohio (Oberlin College and Western Reserve Univ.), did his pediatric training in Chicago and Cleveland, and his pediatric neurology residency at the Johns Hopkins Hospital. After completing his training, Dr Singer remained on the active faculty at Hopkins for 45 years. He was Director of Pediatric Neurology from 1991 - 2011. He was the first recipient (2013) of the Child Neurology Society's Blue Bird Circle Training Program Director Award and a Hower Award lecturer (2016). His clinical research interests include movement disorders, especially Tourette syndrome, stereotypic movements, and proposed autoimmune disorders. His translational research-oriented laboratory focuses on the neurobiology of stereotypic movements and tics. He has been the recipient of federal and private grants, authored numerous original articles, chapters, and three books. He enjoys biking, travel, visiting his five grandchildren, and work.