Protein Folding, Misfolding, and Disease
Methods and Protocols
(Sprache: Englisch)
Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current...
Jetzt vorbestellen
versandkostenfrei
Buch (Gebunden)
Fr. 118.00
inkl. MwSt.
- Kreditkarte, Paypal, Rechnungskauf
- 30 Tage Widerrufsrecht
Produktdetails
Produktinformationen zu „Protein Folding, Misfolding, and Disease “
Klappentext zu „Protein Folding, Misfolding, and Disease “
Protein misfolding is a key feature of many disorders in humans, given that over twenty proteins are known to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of -the-art technologies. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field.
Inhaltsverzeichnis zu „Protein Folding, Misfolding, and Disease “
1. Strategies for Boosting the Accumulation of Correctly Folded Recombinant Proteins Expressed in Escherichia coli; Ario de Marco 2. An Escherichia coli Cell-Free System for Recombinant Protein Synthesis on a Milligram Scale; Luke A. Miles, Gabriela A.N. Crespi, Han Sen, Andrew F. Hill, and Michael W. Parker
3. Synthesis of Peptide Sequences Derived from Fibril-Forming Proteins; Denis B. Scanlon and John A. Karas
4. Refolding Your Protein with a Little Help from REFOLD; Jennifer Phan, Nasrin Yamout, Jason Schmidberger, Stephen P. Bottomley, and Ashley M. Buckle
5. Circular Dichroism and Its Use in Protein Folding Studies; David T. Clarke
6. Distance Measurements by Continuous Wave EPR Spectroscopy to Monitor Protein Folding; James A. Cooke and Louise J. Brown
7. Solution-State Nuclear Magnetic Resonance Spectroscopy and Protein Folding; Lisa D. Cabrita, Christopher A. Waudby, Christopher M. Dobson, and John Christodoulou
8. Diagnostics for Amyloid Fibril Formation: Where to Begin; Danny M. Hatters and Michael D. Griffin
9. Probing Protein Aggregation with Quartz Crystal Microbalances; Tuomas P.J. Knowles, Glyn L. Devlin, Christopher M. Dobson, and Mark E. Welland
10. Dried and Hydrated X-Ray Scattering Analysis of Amyloid Fibrils; Sally L. Gras and Adam M. Squires
11. Solid-State NMR of Amyloid Membrane Interactions; John D. Gehman and Frances Separovic
12. Sedimentation Velocity Analysis of Amyloid Fibrils; Chi Le Lan Pham, Yee-Foong Mok, and Geoffrey J. Howlett
13. Transmission Electron Microscopy of Amyloid Fibrils; Sally L. Gras, Lynne J. Waddington, and Kenneth N. Goldie
14. Surface Plasmon Resonance Spectroscopy: A New Lead in Studying the Membrane Binding of Amyloidogenic Transthyretin; Xu Hou, David H. Small, and Marie-Isabel Aguilar
15. Elucidating the Role of Metals in Alzheimer's Disease through the Use of Surface Enhanced Laser Desorption / Ionisation Time-of-Flight Mass
... mehr
Spectrometry; Andrew D. Watt, Keyla A. Perez, and Lin Wai Hung
... weniger
Bibliographische Angaben
- 2011, 249 Seiten, Masse: 18,5 x 26,2 cm, Gebunden, Englisch
- Herausgegeben: Andrew F Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai
- Verlag: Springer, Berlin
- ISBN-10: 1603272216
- ISBN-13: 9781603272216
- Erscheinungsdatum: 01.07.2011
Sprache:
Englisch
Kommentar zu "Protein Folding, Misfolding, and Disease"
0 Gebrauchte Artikel zu „Protein Folding, Misfolding, and Disease“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "Protein Folding, Misfolding, and Disease".
Kommentar verfassen