Steroid Hormone Receptors: Basic and Clinical Aspects

I Introduction.- 1 Steroid/Nuclear Receptor Superfamily: Recent Advances and Relation to Health and Disease.- II Steroid Receptor Interactions with DNA and Nuclear Components.- 2 Structural and Functional Studies of Selective DNA Binding by Steroid/Nuclear Receptors.- 3 Estrogen Receptor Induced DNA Bending.- 4 The Nuclear Environment and Estrogen Action.- 5 Functional Interaction of the Estrogen Receptor with the Tissue-Specific, Homeodomain Transcription Factor, PIT-1.- 6 Insights into the Genomic Mechanism of Action of 1, 25-Dihydroxyvitamin D3.- 7 Molecular Mechanisms of Thyroid Hormone and Retinoic Acid Action.- III Receptor Structure and Associated Proteins.- 8 Heat Shock Proteins and the Cytoplasmic-Nuclear Trafficking of Steroid Receptors.- 9 In Vitro Assembly of the Avian Progesterone Receptor.- 10 Steroid Receptor Associated Proteins: Heat Shock Protein 90 and P59 Immunophilin.- 11 Estrogenic and Developmental Regulation of 90-Kilodalton Heat Shock Protein Gene Expression.- IV Receptor Modification and Hormone/Antihormone Interactions.- 12 Phosphorylation and Progesterone Receptor Function.- 13 Estrogen Receptor Activation by Ligand-Dependent and Ligand-Independent Pathways.- 14 Why Are Steroid Receptor Antagonists Sometimes Agonists?.- 15 Ligand Requirements for Estrogen Receptor Function and the Actions of Antiestrogens.- V Steroid Receptors and Clinical Correlations.- 16 Molecular Biological Aspects of the Human Androgen Receptor Relating to Disease.- 17 Estrogen Receptor Variants in Breast Cancer.- VI Emerging and Novel Systems.- 18 Human Bone Cells: Newly Discovered Target Cells for Sex Steroids.- 19 Characteristics of the Human Estrogen Receptor Protein Produced in Microbial Expression Systems.- 20 The Ah Locus: A Review.- Author Index.