Synovial Fluid Analysis and The Evaluation of Patients With Arthritis

Chapter 1. The impact of synovial fluid analysis on clinical practice - Introduction.- Chapter 2. Synovial structure and physiology in health and disease.- Chapter 3. Arthrocentesis.- Chapter 4. Biochemical Composition of Synovial Fluid in Health and Disease.- Chapter 5. Cellular Components of Synovial Fluid in Health and Disease.- Chapter 6. Microbiology and Culture Identification of Infections.- Chapter 7. Molecular Microbiology for Diagnosing Infectious Arthritis.- Chapter 8. Basics of Light Microscopic analysis of Synovial Fluid.- Chapter 9. Basics of Polarized light microscopy.- Chapter 10. Crystal associated arthritis: Gout.- Chapter 11. Crystal associated arthritis: Calcium pyrophosphate arthritis.- Chapter 12. Lipid crystals.- Chapter 13. Analytic methods to detect articular basic calcium phosphate crystals.- Chapter 14. Novel Techniques for Synovial Fluid Crystal Analysis.- Chapter 15. Atlas of Images--Normal and Abnormal Synovial Fluid.

Brian Mandell is Professor and Chairman of Academic Medicine and a Senior Staff Physician in Rheumatology and Immunologic Diseases, Center for Vasculitis Care and Research at the Cleveland Clinic. He is Editor in Chief of the Cleveland Clinic Journal of Medicine. He is a Master of the American College of Physicians and the American College of Rheumatology

Dr. Mandell joined the Cleveland Clinic in 1993 following a faculty appointment at the Hospital of the University of Pennsylvania and Chief of Rheumatology at the Graduate Hospital in Philadelphia, PA.  He previously earned a BA in Biology and a PhD in Physiology and Biophysics from Washington University, St. Louis, and then a Medical Degree from New York University School of Medicine.  He trained in medicine and rheumatology at the University of Pennsylvania. He is board certified in Internal Medicine and Rheumatology. He served as interim Director of Inflammation Research and Exploratory Clinical Pharmacology at CIBA Pharmaceuticals.

He is currently Editor-in-Chief of the Cleveland Clinic Journal of Medicine and is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. He previously served as the Director of the Cleveland Clinic Internal Medicine Residency's Scholarly Activity and Medical Humanities Programs.  He is a graduate of the Stanford Faculty Development Program in clinical teaching. He completed a term as member of the Cleveland Clinic's Board of Governors.

Dr. Mandell has served on national education planning and writing committees for the American College of Rheumatology (ACR), the American Board of Internal Medicine (ABIM) and the American College of Physicians (ACP), including serving as chairman of the Annual Meeting Planning Committee for both the ACP and ACR.  He served as Vice Chairman of the ACGME Internal Medicine Residency Review Committee (RRC) until 2019. He has